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	<title>Comments on: Drug company payouts to local doctors</title>
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	<link>http://www.secretsofthecity.com/mnspeak/10455</link>
	<description>Minneapolis + St. Paul</description>
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		<title>By: blipster</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88408</link>
		<dc:creator>blipster</dc:creator>
		<pubDate>Tue, 05 Jun 2007 21:20:07 +0000</pubDate>
		<guid isPermaLink="false">#comment-88408</guid>
		<description>No one expects the Spanish Inquisition!&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
aaaaand we&#039;re at 100...</description>
		<content:encoded><![CDATA[<p>No one expects the Spanish Inquisition!</p>
<p>
aaaaand we&#8217;re at 100&#8230;</p>
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		<title>By: wayne</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88203</link>
		<dc:creator>wayne</dc:creator>
		<pubDate>Tue, 05 Jun 2007 16:27:28 +0000</pubDate>
		<guid isPermaLink="false">#comment-88203</guid>
		<description>competition is great unless there&#039;s an opportunity for republicans to screw with the laws to benefit their rich friends in industry, who will in turn give them lots of money to get reelected because they&#039;re rolling in cash they made from the screwed-up market conditions their republican buddies set up.</description>
		<content:encoded><![CDATA[<p>competition is great unless there&#8217;s an opportunity for republicans to screw with the laws to benefit their rich friends in industry, who will in turn give them lots of money to get reelected because they&#8217;re rolling in cash they made from the screwed-up market conditions their republican buddies set up.</p>
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		<title>By: Spider</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88149</link>
		<dc:creator>Spider</dc:creator>
		<pubDate>Tue, 05 Jun 2007 14:36:06 +0000</pubDate>
		<guid isPermaLink="false">#comment-88149</guid>
		<description>Yo Booby!&lt;br /&gt;
&lt;br /&gt;
You want Phizer to decide what you take and for how much? &lt;br /&gt;
&lt;br /&gt;
How about COMPETITION? Let the drugs come in from all over. Isn&#039;t that what you right-wing wingnuts cry about all the time?</description>
		<content:encoded><![CDATA[<p>Yo Booby!</p>
<p>You want Phizer to decide what you take and for how much? </p>
<p>How about COMPETITION? Let the drugs come in from all over. Isn&#8217;t that what you right-wing wingnuts cry about all the time?</p>
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		<title>By: mnblrmkr</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88135</link>
		<dc:creator>mnblrmkr</dc:creator>
		<pubDate>Tue, 05 Jun 2007 06:04:43 +0000</pubDate>
		<guid isPermaLink="false">#comment-88135</guid>
		<description>Well, since I&#039;m not on Lipitor, I guess I don&#039;t have to worry...Though that might strip clubs superfluous.&lt;br /&gt;
&lt;br /&gt;
But, yeah, if another Vioxx situation were to arise, I&#039;d reconsider. I didn&#039;t say I couldn&#039;t be convinced. I just haven&#039;t seen any thing that would so far.</description>
		<content:encoded><![CDATA[<p>Well, since I&#8217;m not on Lipitor, I guess I don&#8217;t have to worry&#8230;Though that might strip clubs superfluous.</p>
<p>But, yeah, if another Vioxx situation were to arise, I&#8217;d reconsider. I didn&#8217;t say I couldn&#8217;t be convinced. I just haven&#8217;t seen any thing that would so far.</p>
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		<title>By: aliecat</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88128</link>
		<dc:creator>aliecat</dc:creator>
		<pubDate>Tue, 05 Jun 2007 05:23:01 +0000</pubDate>
		<guid isPermaLink="false">#comment-88128</guid>
		<description>What if Lipitor caused man boobs?  Would that do it for you?  Hee hee!</description>
		<content:encoded><![CDATA[<p>What if Lipitor caused man boobs?  Would that do it for you?  Hee hee!</p>
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		<title>By: mnblrmkr</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88123</link>
		<dc:creator>mnblrmkr</dc:creator>
		<pubDate>Tue, 05 Jun 2007 04:14:46 +0000</pubDate>
		<guid isPermaLink="false">#comment-88123</guid>
		<description>&lt;em&gt;&quot;Is the risk of muscle problems and/or liver problems worth the risk when it has not been shown to be a benefit to those WITHOUT heart disease?&quot;&lt;/em&gt;&lt;br /&gt;
&lt;br /&gt;
That&#039;s why you have periodic blood work. And really, the risks aren&#039;t that great. In fact, a 10mg dose of simvastatin can be obtained OTC in the UK.&lt;br /&gt;
&lt;br /&gt;
People with multiple risk factors, can expect similar benefits as those with heart disease, even if they do not currently have heart disease.&lt;br /&gt;
&lt;br /&gt;
&lt;em&gt;Further, only Lipitor has been shown to have this benefit the rest have not.&lt;/em&gt;&lt;br /&gt;
&lt;br /&gt;
Simvastatin (zocor, vytorin) has also received the same approval by the  FDA as lipitor. Not surprising, as they both target the same enzyme in the cholesterol synthesis pathway,as do the other statins. &lt;br /&gt;
&lt;br /&gt;
&lt;em&gt;&quot;I was just pointing out the facts, I didn&#039;t expect some sort of Spanish Inquisition...&quot;&lt;/em&gt;&lt;br /&gt;
&lt;br /&gt;
No inquisition. I jsut felt you were over stating the risks, and understating the benefits.&lt;br /&gt;
&lt;br /&gt;
Sure, not everyone with high cholesterol will develop heart disease, nor does everyone who smokes, even for decades, develop lung cancer, but they are both significant risk factors that increase the chances.&lt;br /&gt;
&lt;br /&gt;
As I said, I havne&#039;t seen anythingthat would convince me to stop filling my scrip.&lt;br /&gt;
</description>
		<content:encoded><![CDATA[<p><em>&#8220;Is the risk of muscle problems and/or liver problems worth the risk when it has not been shown to be a benefit to those WITHOUT heart disease?&#8221;</em></p>
<p>That&#8217;s why you have periodic blood work. And really, the risks aren&#8217;t that great. In fact, a 10mg dose of simvastatin can be obtained OTC in the UK.</p>
<p>People with multiple risk factors, can expect similar benefits as those with heart disease, even if they do not currently have heart disease.</p>
<p><em>Further, only Lipitor has been shown to have this benefit the rest have not.</em></p>
<p>Simvastatin (zocor, vytorin) has also received the same approval by the  FDA as lipitor. Not surprising, as they both target the same enzyme in the cholesterol synthesis pathway,as do the other statins. </p>
<p><em>&#8220;I was just pointing out the facts, I didn&#8217;t expect some sort of Spanish Inquisition&#8230;&#8221;</em></p>
<p>No inquisition. I jsut felt you were over stating the risks, and understating the benefits.</p>
<p>Sure, not everyone with high cholesterol will develop heart disease, nor does everyone who smokes, even for decades, develop lung cancer, but they are both significant risk factors that increase the chances.</p>
<p>As I said, I havne&#8217;t seen anythingthat would convince me to stop filling my scrip.</p>
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		<title>By: DouglasG</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88112</link>
		<dc:creator>DouglasG</dc:creator>
		<pubDate>Tue, 05 Jun 2007 02:31:54 +0000</pubDate>
		<guid isPermaLink="false">#comment-88112</guid>
		<description>To quote that link:&lt;br /&gt;
&lt;br /&gt;
&lt;em&gt;1994 study called the Scandinavian Simvastatin Survival Study (also called 4S) found that lowering cholesterol can prevent heart attacks and reduce death in men and women &lt;B&gt;who already have heart disease and high cholesterol.&lt;/B&gt;&lt;/em&gt;  (Emphasis mine.)&lt;br /&gt;
&lt;br /&gt;
Is the risk of  &lt;a href=&quot;http://www.lipitor.com/learn-about-lipitor/lipitor-safety-profile.jsp?setShowOn=../learn-about-lipitor/home.jsp&amp;setShowHighlightOn=../learn-about-lipitor/lipitor-safety-profile.jsp&quot; target=&quot;_blank&quot;&gt;muscle problems and/or liver problems&lt;/a&gt; worth the risk when it has not been shown to be a benefit to those WITHOUT heart disease?  Further, only Lipitor has been shown to have this benefit the rest have not.&lt;br /&gt;
&lt;br /&gt;
I was just pointing out the facts, I didn&#039;t expect some sort of Spanish Inquisition...</description>
		<content:encoded><![CDATA[<p>To quote that link:</p>
<p><em>1994 study called the Scandinavian Simvastatin Survival Study (also called 4S) found that lowering cholesterol can prevent heart attacks and reduce death in men and women <b>who already have heart disease and high cholesterol.</b></em>  (Emphasis mine.)</p>
<p>Is the risk of  <a href="http://www.lipitor.com/learn-about-lipitor/lipitor-safety-profile.jsp?setShowOn=../learn-about-lipitor/home.jsp&#038;setShowHighlightOn=../learn-about-lipitor/lipitor-safety-profile.jsp" target="_blank">muscle problems and/or liver problems</a> worth the risk when it has not been shown to be a benefit to those WITHOUT heart disease?  Further, only Lipitor has been shown to have this benefit the rest have not.</p>
<p>I was just pointing out the facts, I didn&#8217;t expect some sort of Spanish Inquisition&#8230;</p>
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		<title>By: bobby_b</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88098</link>
		<dc:creator>bobby_b</dc:creator>
		<pubDate>Mon, 04 Jun 2007 23:42:55 +0000</pubDate>
		<guid isPermaLink="false">#comment-88098</guid>
		<description>No, he&#039;s just pining for the fjords.&lt;br /&gt;
&lt;br /&gt;
(Yes, that was gratuitous.  I leave and the Python jokes start.)  &lt;br /&gt;
&lt;br /&gt;
</description>
		<content:encoded><![CDATA[<p>No, he&#8217;s just pining for the fjords.</p>
<p>(Yes, that was gratuitous.  I leave and the Python jokes start.)  </p>
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		<title>By: bobby_b</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88097</link>
		<dc:creator>bobby_b</dc:creator>
		<pubDate>Mon, 04 Jun 2007 23:31:33 +0000</pubDate>
		<guid isPermaLink="false">#comment-88097</guid>
		<description>&quot;&lt;em&gt;Maybe a third party (government? universities?) should be more involved in navigating that relationship.&lt;/em&gt;&quot;&lt;br /&gt;
&lt;br /&gt;
Uh huh. I want John Murtha, Barbara Boxer, and Alcee Hastings deciding which drugs I should be taking.  (&quot;Well, which manufacturer has the best diversity program, puts up the most global warming posters, and has contributed the most to our re-election campaign?&quot;&lt;br /&gt;
&lt;br /&gt;
Universities are already at the head of the grant lists for drug research.  They represent one part of the competition as entities work to develop drugs.  Giving them a larger role would simply make them the BSD among to competitors, and, again, I do not think that goverment as BSD ever really benefits people outside of government.</description>
		<content:encoded><![CDATA[<p>&#8220;<em>Maybe a third party (government? universities?) should be more involved in navigating that relationship.</em>&#8220;</p>
<p>Uh huh. I want John Murtha, Barbara Boxer, and Alcee Hastings deciding which drugs I should be taking.  (&#8221;Well, which manufacturer has the best diversity program, puts up the most global warming posters, and has contributed the most to our re-election campaign?&#8221;</p>
<p>Universities are already at the head of the grant lists for drug research.  They represent one part of the competition as entities work to develop drugs.  Giving them a larger role would simply make them the BSD among to competitors, and, again, I do not think that goverment as BSD ever really benefits people outside of government.</p>
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		<title>By: mnblrmkr</title>
		<link>http://www.secretsofthecity.com/mnspeak/10455#comment-88094</link>
		<dc:creator>mnblrmkr</dc:creator>
		<pubDate>Mon, 04 Jun 2007 23:14:11 +0000</pubDate>
		<guid isPermaLink="false">#comment-88094</guid>
		<description>&quot;Until they can positively link Lipitor and the rest of those cholesterol reducing drugs to ACTUALLY preventing heart disease no one should be taking them! They have been shown to help for people WITH heart disease, but high cholesterol does not mean that heart disease is immanent. Some people have naturally high cholesterol numbers, but that does not necessarily translate into a build-up of plaque in the arteries.&quot;&lt;br /&gt;
&lt;br /&gt;
I&#039;d say the &lt;a href=&quot;http://www.nhlbi.nih.gov/chd/why4.htm&quot; target=&quot;_blank&quot;&gt;evidence &lt;/a&gt;for their benefits is pretty strong. Certainly strong enough for me to not quit filling my script.</description>
		<content:encoded><![CDATA[<p>&#8220;Until they can positively link Lipitor and the rest of those cholesterol reducing drugs to ACTUALLY preventing heart disease no one should be taking them! They have been shown to help for people WITH heart disease, but high cholesterol does not mean that heart disease is immanent. Some people have naturally high cholesterol numbers, but that does not necessarily translate into a build-up of plaque in the arteries.&#8221;</p>
<p>I&#8217;d say the <a href="http://www.nhlbi.nih.gov/chd/why4.htm" target="_blank">evidence </a>for their benefits is pretty strong. Certainly strong enough for me to not quit filling my script.</p>
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